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It has been argued that its origin liesin a series of conflicts among psychiatrists, psychoanalysts and clinical psychologists (Strand2011). Lin J, Chen J, Elenbaas B, Levine AJ (1994) Several hydrophobic amino acids in the p53amino-terminal domain are required for transcriptional activation, binding to mdm-2 and theadenovirus 5 E1B 55 kD protein

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